ESMO Asia 2026丨瞭望前瞻,42项中国乳腺癌研究闪耀狮城,不止参与,更是主角

2026年欧洲肿瘤内科学会亚洲年会(ESMO Asia 2026)将于2026年12月4日至6日举办,本次会议是亚太地区肿瘤学领域的年度学术盛会,旨在汇聚全球顶尖专家,分享前沿科研成果与临床实践智慧。目前会议入选研究标题已正式公布,其中乳腺癌领域共有42项中国研究入选,涵盖4项口头报告及38项壁报,《肿瘤瞭望》特将研究信息整理如下,以供参考,如有疏漏,敬请留言指正。

编者按:2026年欧洲肿瘤内科学会亚洲年会(ESMO Asia 2026)将于2026年12月4日至6日举办,本次会议是亚太地区肿瘤学领域的年度学术盛会,旨在汇聚全球顶尖专家,分享前沿科研成果与临床实践智慧。目前会议入选研究标题已正式公布,其中乳腺癌领域共有42项中国研究入选,涵盖4项口头报告及38项壁报,《肿瘤瞭望》特将研究信息整理如下,以供参考,如有疏漏,敬请留言指正。

Proffered Paper(优选口头报告)

摘要号:3O

英文标题:Neoadjuvant trastuzumab deruxtecan followed by paclitaxel + trastuzumab +pertuzumab (T-DXd-THP) vs dose-dense doxorubicin + cyclophosphamide followed byTHP (ddAC-THP) in East Asian patients with high-risk, HER2+ early-stage breast cancer(eBC): A DESTINY-Breast11 (DB-11) analysis

中文标题:高危HER2阳性早期乳腺癌东亚患者新辅助T-DXd序贯THP对比剂量密集ddAC序贯THP:DESTINY-Breast11(DB-11)研究分析

讲者:吴炅 复旦大学附属肿瘤医院

时间:Fri,Dec4,2026 11:23-11:33

地点:Hall 401

摘要号:4O

英文标题:Trastuzumab deruxtecan (T-DXd) vs trastuzumab emtansine (T-DM1) in patients (pts)from Asia with human epidermal growth factor receptor 2-positive (HER2+) residualinvasive early breast cancer (eBC) after neoadjuvant therapy (NAT): DESTINY-Breast05(DB-05) subgroup analysis

中文标题:新辅助治疗后HER2阳性残留浸润性早期乳腺癌亚洲患者T-DXd对比T-DM1:DESTINY-Breast05(DB-05)研究亚组分析

讲者:黄俊升 台湾大学医学院附设医院

时间:Fri,Dec4,2026 11:33-11:43

地点:Hall 401

Rapid Oral(快速口头报告)

摘要号:95RO

英文标题:First-line (1L) datopotamab deruxtecan (Dato-DXd) vs chemotherapy in patientswith locally recurrent inoperable or metastatic triple-negative breast cancer for whomimmunotherapy was not an option: Results from the TROPION-Breast02 Chinese cohort

中文标题:Dato-DXd对比化疗用于免疫治疗不可用的局部复发不可手术或转移性三阴性乳腺癌一线治疗:TROPION-Breast02研究中国队列结果

讲者:邵志敏 复旦大学附属肿瘤医院

时间:Sat,Dec5,2026 14:35-14:40

地点:Hall 401

摘要号:99RO

英文标题:Trastuzumab deruxtecan plus pyrotinib in first-line HER2-positive unresectable ormetastatic breast cancer: interim analysis of the TROPHY study

中文标题:T-DXd联合吡咯替尼一线治疗HER2阳性不可切除或转移性乳腺癌:TROPHY研究中期分析

讲者:樊英 中国医学科学院肿瘤医院

时间:Sat,Dec5,2026 15:22-15:27

地点:Hall 401

Poster&ePoster(壁报及电子壁报)

摘要号:10P

英文标题:Prognostic Analysis of De-escalated Axillary Surgery in HR+/HER2−, cN0 BreastCancer Patients Undergoing Breast-Conserving Surgery

中文标题:HR+/HER2-、cN0期保乳乳腺癌患者腋窝手术降阶梯的预后分析

讲者:Luning Yang (Kunming, CN)

摘要号:13P

英文标题:Standard imaging-guided, Doppler-free chest wall perforator flap reconstruction forgranulomatous lobular mastitis: A simplified approach for resource-limited settings

中文标题:标准影像引导无多普勒胸壁穿支皮瓣重建治疗肉芽肿性小叶性乳腺炎:一种适用于资源有限场景的简化方案

讲者:Ziying Wang (Nanjing, CN)

摘要号:15P

英文标题:Real-World Study: Prognosis and Quality of Life Assessment of Breast CancerPatients Undergoing Breast-Conserving Surgery and Total Mastectomy in Xinjiang Region

中文标题:真实世界研究:新疆地区乳腺癌患者保乳手术与全乳切除术后的预后及生活质量评估

讲者:Shengjie Liu (Urumqi, CN)

摘要号:18P

英文标题:Non-estradiol hormonal profiling reveals pituitary-axis activation patterns beyondestradiol suppression during GnRHa plus exemestane therapy

中文标题:非雌二醇激素谱揭示GnRHa联合依西美坦治疗中超出雌二醇抑制的垂体轴激活模式

讲者:薛聪 中山大学肿瘤防治中心

摘要号:20P

英文标题:Health-related quality of life (HRQoL) with adjuvant dalpiciclib plus endocrine therapyin patients with hormone receptor-positive (HR+), HER2-negative (HER2–), earlyintermediate-to-high-risk breast cancer: Results from a multicenter, two-cohort phase 2trial

中文标题:达尔西利联合内分泌治疗辅助治疗HR+/HER2-早期中高危乳腺癌患者的健康相关生活质量:一项多中心、双队列II期试验结果

讲者:徐贵颖 吉林省肿瘤医院

摘要号:27P

英文标题:Real-world perioperative treatment patterns for HER2+ early-stage breast cancer(eBC) in China

中文标题:中国HER2阳性早期乳腺癌围手术期治疗模式的真实世界研究

讲者:王佳玉 中国医学科学院肿瘤医院

摘要号:32P

英文标题: Neoadjuvant Pyrotinib Monotherapy in HER2-Positive Ductal Carcinoma In Situ: APhase II Single-Arm Study

中文标题:新辅助吡咯替尼单药治疗HER2阳性导管原位癌:一项II期单臂研究

讲者:何佳玲 陆军军医大学西南医院

摘要号:35P

英文标题:Targeting DDX5 with tetraarsenic tetrasulfide overcomes cisplatin resistance intriple-negative breast cancer

中文标题:四硫化四砷靶向DDX5逆转三阴性乳腺癌顺铂耐药

讲者:Zhiyi Liu (Shanghai, CN)

摘要号:43P

英文标题:Expression Patterns, Prognostic Values and Underlying Mechanisms of Diabetes-Related Genes in Breast Cancer

中文标题:糖尿病相关基因在乳腺癌中的表达模式、预后价值及作用机制

讲者:Yu Zhou (Fuzhou, CN)

摘要号:46P

英文标题:Harnessing Frequency-Aware Deep Architectures and Hybrid Feature Fusion forRobust Rare Cell Identification in Clinical Fluorescence Microscopy

中文标题:基于频率感知深度架构与混合特征融合的临床荧光显微罕见细胞精准识别

讲者:Jiao-Mei Gong (Zhengzhou, CN)

摘要号:55eP

英文标题:World Effectiveness of Abemaciclib in Chinese Patients with Breast Cancer: A2‑Year Follow‑Up

中文标题:阿贝西利在中国乳腺癌患者中的真实世界疗效:2年随访结果

讲者:刘强 中山大学孙逸仙纪念医院

摘要号:56eP

英文标题:PIK3CA mutation spectrum and clinicopathological associations in early-stagehormone receptor-positive breast cancer: an interim analysis

中文标题:早期HR阳性乳腺癌PIK3CA突变谱与临床病理特征的关联:中期分析

讲者:颜蕴文 安徽医科大学第一附属医院

摘要号:60eP

英文标题:Genomic Drivers and Prognostic Biomarkers in Breast Cancer: Insights from Large-Scale Sequencing Cohorts

中文标题:乳腺癌基因组驱动因素与预后生物标志物:来自大规模测序队列的启示

讲者:Longyan Xie (Shanghai, CN)

摘要号:68P

英文标题:Total examined axillary lymph nodes as an independent predictor of pathologicalcomplete response after neoadjuvant therapy in ER+/HER2– breast cancer: a retrospectivemulticenter analysis

中文标题:腋窝淋巴结清扫总数作为ER+/HER2-乳腺癌新辅助治疗后病理完全缓解的独立预测因素:一项回顾性多中心分析

讲者:吕文杰 上海交通大学医学院附属新华医院

摘要号:77P

英文标题:Deep Learning for Early Prediction of Breast Cancer Response to NeoadjuvantTherapy Using Dynamic Contrast-enhanced Ultrasound Videos

中文标题:基于动态对比增强超声视频的深度学习早期预测乳腺癌新辅助治疗疗效

讲者:Liting Feng (Chengdu, CN)

摘要号:85P

英文标题:Interpretable CoxPH-centered machine learning models for predicting cancer-specific survival and treatment-associated survival patterns in stage II-III triple-negativebreast cancer

中文标题:基于可解释CoxPH的机器学习模型预测II-III期三阴性乳腺癌肿瘤特异性生存及治疗相关生存模式

讲者:Sirui Zhu (Beijing, CN)

摘要号:104P

英文标题:Real-World Effectiveness and Safety of Inavolisib-Based Therapy in Chinese Patients with HR+/HER2− Advanced Breast Cancer: A Multicenter Study

中文标题:伊那利塞为基础的方案治疗中国HR+/HER2-晚期乳腺癌患者的真实世界疗效与安全性:一项多中心研究

讲者:梁旭 北京大学肿瘤医院

摘要号:106P

英文标题:Baseline genomic landscape associated with early progression during first-lineCDK4/6 inhibitor-based endocrine therapy in HR+/HER2− metastatic breast cancer: anexploratory whole-exome sequencing study

中文标题:HR+/HER2-转移性乳腺癌一线CDK4/6抑制剂联合内分泌治疗早期进展相关的基线基因组图谱:一项探索性全外显子测序研究

讲者:杨庄青 云南省肿瘤医院

摘要号:108P

英文标题:Real‑world effectiveness and safety of Dalpiciclib in elderly patients with hormonereceptor‑positive advanced breast cancer: a multi-center retrospective study

中文标题:达尔西利治疗老年HR阳性晚期乳腺癌患者的真实世界疗效与安全性:一项多中心回顾性研究

讲者:Mengran Xu (Hefei, CN)

摘要号:111P

英文标题:Real-World Efficacy and Safety of Inavolisib Combined with Various CDK4/6Inhibitors in PIK3CA-Mutated, HR+/HER2− Advanced Breast Cancer

中文标题:伊那利塞联合不同CDK4/6抑制剂治疗PIK3CA突变HR+/HER2-晚期乳腺癌的真实世界疗效与安全性

讲者:农巧红 北京大学深圳医院

摘要号:112P

英文标题:Real-World analysis of Inavolisib-based therapy in advanced breast cancer patientswith PIK3CA mutations in China

中文标题:伊那利塞为基础的方案治疗中国PIK3CA突变晚期乳腺癌患者的真实世界分析

讲者:宋玉华 青岛大学附属医院

摘要号:115P

英文标题:Real-world data on safety of switching to trastuzumab rezetecan after discontinuation of other HER2-directed antibody-drug conjugates, primarily trastuzumab deruxtecan, due to adverse events in advanced HER2-positive/low breast cancer

中文标题:晚期HER2阳性/低表达乳腺癌患者因不良事件停用其他靶向HER2 ADC(主要为T-DXd)后换用瑞康曲妥珠单抗的安全性真实世界数据

讲者:欧阳取长 湖南省肿瘤医院

摘要号:116P

英文标题:Early dynamic ⁶⁸Ga-HER2 PET/CT for predicting clinical benefit of anti-HER2 therapyin advanced HER2-positive breast cancer: Head-to-head comparison with RECIST 1.1 and¹⁸F-FDG PET/CT

中文标题:早期动态⁶⁸Ga-HER2 PET/CT预测晚期HER2阳性乳腺癌抗HER2治疗临床获益:与RECIST1.1及¹⁸F-FDG PET/CT的头对头比较

讲者:缪海韬 复旦大学附属肿瘤医院

摘要号:119P

英文标题:Real-world study of different anti-HER2 treatment strategies in first-line HER2-positive advanced breast cancer

中文标题:HER2阳性晚期乳腺癌一线不同抗HER2治疗策略的真实世界研究

讲者:Yuqing Chen (Kunming, CN)

摘要号:120P

英文标题:Trop-2 Expression Level and Efficacy of Trop-2–Targeted Antibody–DrugConjugates in Patients With Advanced Breast Cancer: A Systematic Review and Meta-Analysis

中文标题:晚期乳腺癌患者Trop-2表达水平与靶向Trop-2 ADC疗效的相关性:一项系统评价与荟萃分析

讲者:彭上轩 台湾大学医学院附设医院云林分院

摘要号:121P

英文标题:Predictive value of obesity and serum non-esterified fatty acid (NEFA) in patientswith metastatic triple-negative breast cancer receiving PD-1 blockade

中文标题:肥胖及血清非酯化脂肪酸对接受PD-1抑制剂治疗的转移性三阴性乳腺癌患者的预测价值

讲者:谢一兆 复旦大学附属肿瘤医院

摘要号:122P

英文标题:Survival improvement in the immune checkpoint inhibitor-introduction era andresidual prognostic value of lymph node burden in triple-negative breast cancer

中文标题:免疫检查点抑制剂时代三阴性乳腺癌的生存改善及淋巴结负荷的残留预后价值

讲者:Linjie Fan (Beijing, CN)

摘要号:123P

英文标题:A Lactate–Lactylation Decoupling Program Silences AKR1C1 via HDAC1 to DriveCisplatin Resistance in Triple-Negative Breast Cancer

中文标题:乳酸-乳酸化失偶联程序通过HDAC1沉默AKR1C1介导三阴性乳腺癌顺铂耐药

讲者:Yawei Zhao (Shanghai, CN)

摘要号:124P

英文标题:Upfront versus delayed radiotherapy in breast cancer brain metastases: A real-world cohort study

中文标题:乳腺癌脑转移患者即刻与延迟放疗的对比:一项真实世界队列研究

讲者:Hang Zao (Urumqi, CN)

摘要号:128P

英文标题:RALA-RALBP1 axis activates endothelial RAC1/NF-κB signaling to promote breastcancer metastasis

中文标题:RALA-RALBP1轴通过激活内皮细胞RAC1/NF-κB信号通路促进乳腺癌转移

讲者:Qian Huang (Xi'an, CN)

摘要号:131P

英文标题:Tetrastigma hemsleyanum polysaccharide suppresses breast cancer stem cells-driven metastatic by targeting the CDCP1/NF-κB/NACC1 axis

中文标题:三叶青多糖通过靶向CDCP1/NF-κB/NACC1轴抑制乳腺癌干细胞介导的转移

讲者:Si Wentao (Nanjing, CN)

摘要号:133P

英文标题: Identification of E3 Ubiquitin Ligase-Related Genes in Triple-Negative Breast Cancerand Analysis of Their Regulatory Networks and Clinical Implications

中文标题:三阴性乳腺癌E3泛素连接酶相关基因的鉴定及其调控网络与临床意义分析

讲者:Yu Zhou (Fuzhou, CN)

摘要号:137TiP

英文标题:A Prospective, Non-Randomized, Open-Label Phase Single-Arm Study of First-Line Low-Dose Nab-Paclitaxel in Combination with Toripalimab and FractionatedStereotactic Radiotherapy (FSRT) for Triple-Negative Breast Cancer with Brain Metastasis

中文标题:低剂量白蛋白紫杉醇联合特瑞普利单抗及分次立体定向放疗一线治疗三阴性乳腺癌脑转移:一项前瞻性、非随机、开放标签单臂研究

讲者:范宇 西南医科大学附属医院

摘要号:138TiP

英文标题:Metronomic Vinorelbine Chemotherapy Combined with Penpulimab and Local Radiotherapy (Hypofractionated Radiotherapy or SBRT/FSRT), With or Without Anlotinib,for Recurrent/Metastatic Triple-Negative Breast Cancer: A Prospective, Single-Arm Study

中文标题:长春瑞滨节拍化疗联合派安普利单抗及局部放疗(大分割放疗或SBRT/FSRT)±安罗替尼治疗复发/转移性三阴性乳腺癌:一项前瞻性单臂研究

讲者:范宇 西南医科大学附属医院

摘要号:140eP

英文标题:PIK3CA-mutated HR+/HER2– advanced breast cancer: A pharmacist-ledmulticenter retrospective observational study

中文标题:PIK3CA突变HR+/HER2-晚期乳腺癌:一项药师主导的多中心回顾性观察性研究

讲者:李曼 大连医科大学附属第二医院

摘要号:142eP

英文标题:Pyrotinib plus dalpiciclib and letrozole in ER-positive/HER2-positive advancedbreast cancer: updated phase II results

中文标题:吡咯替尼联合达尔西利及来曲唑治疗ER阳性/HER2阳性晚期乳腺癌:II期研究更新结果

讲者:陈占红 浙江省肿瘤医院

摘要号:693P

英文标题:Immunometabolic Features and Potential Clinical Value of Ferroptosis–Nucleic AcidMetabolism Coupling in Triple-Negative Breast Cancer

中文标题:三阴性乳腺癌铁死亡-核酸代谢偶联的免疫代谢特征及潜在临床价值

讲者:He Hao (Taiyuan, CN)

摘要号:711eP

英文标题:Multi-omics Integration Reveals a Novel Synergistic Anti-Breast Cancer Mechanism of Trastuzumab Deruxtecan Combined with Lapatinib

中文标题:多组学整合揭示T-DXd联合拉帕替尼抗乳腺癌的新型协同作用机制

讲者:Yijun Li (Xi'an, CN)

摘要号:726eP

英文标题:Preclinical evaluation and target characterization of cyclic peptide C5 in triple-negative breast cancer

中文标题:环肽C5在三阴性乳腺癌中的临床前评价及靶点表征

讲者:Qichen Dai (Beijing, CN)

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